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Article

Schizosaccharomyces pombe Hsp90/Git10 is required for glucose/cAMP signaling.

Genetics - 1 Apr 2008

Alaamery Manal A, Hoffman Charles S

Abstract excerpt

The fission yeast Schizosaccharomyces pombe senses environmental glucose through a cAMP-signaling pathway. Elevated cAMP levels activate protein kinase A (PKA) to inhibit transcription of genes involved in sexual development and gluconeogenesis, including the fbp1(+) gene, which encodes fructose-1,6-bisphosphatase. Glucose-mediated activation of PKA requires the function of nine glucose-insensitive transcription...

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Identifiers

PMID: 18430926
DOI: 10.1534/genetics.107.086165
PMCID: PMC2323787

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Schizosaccharomyces pombe Hsp90/Git10 is required for glucose/cAMP signaling.PMID 18430926Read ↗

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Suppressors of an adenylate cyclase deletion in the fission yeast Schizosaccharomyces pombe.Semantic proximity Read ↗

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Isolation and characterization of mutants constitutive for expression of the fbp1 gene of Schizosaccharomyces pombe.Semantic proximity Read ↗

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Transcriptional regulators of the Schizosaccharomyces pombe fbp1 gene include two redundant Tup1p-like corepressors and the CCAAT binding factor activation complex.Semantic proximity Read ↗

Six git genes encode a glucose-induced adenylate cyclase activation pathway in the fission yeast Schizosaccharomyces pombe.Semantic proximity Read ↗

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