Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Schizosaccharomyces pombe Git1 is a C2-domain protein required for glucose activation of adenylate cyclase.

Genetics - 1 May 2006

Kao Richard S, Morreale Eric, Wang Lili, Ivey F Douglas, Hoffman Charles S

Abstract excerpt

Schizosaccharomyces pombe senses environmental glucose through a cAMP-signaling pathway, activating cAMP-dependent protein kinase A (PKA). This requires nine git (glucose insensitive transcription) genes that encode adenylate cyclase, the PKA catalytic subunit, and seven "upstream" proteins required for glucose-triggered adenylate cyclase activation, including three heterotrimeric G-protein subunits and its...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Adenylyl Cyclases
Share to Cyclic AMP
Share to Glucose

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to GTP-Binding Protein gamma Subunits

Share to Schizosaccharomyces

Share to Schizosaccharomyces pombe Proteins

Share to Spores, Fungal

Share to Suppression, Genetic

Source

Open in PubMed Open full text

Identifiers

PMID: 16489217
DOI: 10.1534/genetics.106.055699
PMCID: PMC1461440

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Schizosaccharomyces pombe Git1 is a C2-domain protein required for glucose activation of adenylate cyclase.PMID 16489217Read ↗

Six git genes encode a glucose-induced adenylate cyclase activation pathway in the fission yeast Schizosaccharomyces pombe.Semantic proximity Read ↗

Glucose repression of fbp1 transcription of Schizosaccharomyces pombe is partially regulated by adenylate cyclase activation by a G protein alpha subunit encoded by gpa2 (git8).Semantic proximity Read ↗

Schizosaccharomyces pombe Git7p, a member of the Saccharomyces cerevisiae Sgtlp family, is required for glucose and cyclic AMP signaling, cell wall integrity, and septation.Semantic proximity Read ↗

Schizosaccharomyces pombe adenylate cyclase suppressor mutations suggest a role for cAMP phosphodiesterase regulation in feedback control of glucose/cAMP signaling.Semantic proximity Read ↗

Glucose repression of transcription of the Schizosaccharomyces pombe fbp1 gene occurs by a cAMP signaling pathway.Semantic proximity Read ↗

The fission yeast git5 gene encodes a Gbeta subunit required for glucose-triggered adenylate cyclase activation.Semantic proximity Read ↗

The git5 Gbeta and git11 Ggamma form an atypical Gbetagamma dimer acting in the fission yeast glucose/cAMP pathway.Semantic proximity Read ↗

Schizosaccharomyces pombe Hsp90/Git10 is required for glucose/cAMP signaling.Semantic proximity Read ↗

Direct activation of fission yeast adenylate cyclase by the Gpa2 Galpha of the glucose signaling pathway.Semantic proximity Read ↗

Sck1 negatively regulates Gpa2-mediated glucose signaling in Schizosaccharomyces pombe.Semantic proximity Read ↗

Activated alleles of the Schizosaccharomyces pombe gpa2+ Galpha gene identify residues involved in GDP-GTP exchange.Semantic proximity Read ↗

Suppressors of an adenylate cyclase deletion in the fission yeast Schizosaccharomyces pombe.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.