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Article

A screen for genes involved in respiration control and longevity in Schizosaccharomyces pombe.

Annals of the New York Academy of Sciences - 1 Jun 2010

Roux Antoine E, Arseneault Geneviève, Chartrand Pascal, Ferbeyre Gerardo, Rokeach Luis A

Abstract excerpt

We present results showing that glucose signaling has proaging effects in the yeast Schizosaccharomyces pombe. Deletion of the receptor that senses extracellular glucose (Git3) increases the life span of S. pombe, while constitutive activation of the Galpha subunit acting downstream of this receptor (Gpa2) shortens its life span. The latter mutant is also impaired for growth under respiration conditions. We have...

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PMID: 20536828
DOI: 10.1111/j.1749-6632.2010.05198.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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