Article
Association of HLA-DQ and -DR alleles with protection from or infection with HIV-1.
Experimental and molecular pathology - 1 Feb 2000
Roe D L, Lewis R E, Cruse J M
Abstract excerpt
Infection with human immunodeficiency virus type 1 (HIV-1) and progression to acquired immune deficiency syndrome (AIDS) are controlled by both host genetic factors and viral factors. The HLA (human leukocyte antigen) region in humans controls immune response functions and tissue rejection and influences susceptibility to neoplasia, autoimmune diseases, and infectious diseases including HIV. Twenty-eight African...
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