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Article

Human leucocyte antigen class II DRB1 and DQB1 associations in human immunodeficiency virus-infected patients of Mumbai, India.

International journal of immunogenetics - 1 Jun 2010

Shankarkumar U, Pawar A, Ghosh K, Bajpai S, Pazare A

Abstract excerpt

The pathogenesis of human immunodeficiency virus (HIV) infection clearly involves immunoregulatory host factors and products of major histocompatibility complex class II genes, which present antigenic peptides to the T-cell receptor on CD4+ cells, which in turn increase the production of specific antibodies and cytotoxic T lymphocytes. The main objective of this study was to determine the associations of human...

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PMID: 20345872
DOI: 10.1111/j.1744-313X.2010.00911.x

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