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Article

Activating transcription factor 3: a hormone responsive gene in the etiology of hypospadias.

European journal of endocrinology - 1 May 2008

Beleza-Meireles Ana, Töhönen Virpi, Söderhäll Cilla, Schwentner Christian, Radmayr Christian, Kockum Ingrid, Nordenskjöld Agneta

Abstract excerpt

INTRODUCTION: Hypospadias is a common inborn error of the genital development, whose complex etiology remains elusive. Defects of the androgen metabolism and activity have been found in a subset of boys with hypospadias. Moreover, the balance between androgens and estrogens seems to be important to the proper male genital development. Activating transcription factor 3 (ATF3), an estrogen responsive gene, has been...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18426833
DOI: 10.1530/EJE-07-0793

Genes

ATF3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Activating transcription factor 3: a hormone responsive gene in the etiology of hypospadias.PMID 18426833Read ↗

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Aetiology of hypospadias: a systematic review of genes and environment.Semantic proximity Read ↗

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Role of epigenetics in the etiology of hypospadias through penile foreskin DNA methylation alterationsSemantic proximity Read ↗

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