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Article

Genomic variants of ATF3 in patients with hypospadias.

The Journal of urology - 1 Nov 2008

Kalfa Nicolas, Liu Benchun, Klein Ophir, Wang Ming-Hsieh, Cao Mei, Baskin Laurence S

Abstract excerpt

PURPOSE: ATF3, an estrogen responsive gene expressed during genital development, could be implicated in the etiology of hypospadias. ATF3 is up-regulated in the foreskin of patients with hypospadias and is implicated in suppression of the cell cycle, which may interfere with urethral cell growth. We sought to investigate the sequence of ATF3 in patients with hypospadias. MATERIAL AND METHODS: Direct sequencing of...

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Topics

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Share to Gene Expression Regulation, Developmental
Share to Genitalia, Male

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Hypospadias

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Source

Identifiers

PMID: 18804813
DOI: 10.1016/j.juro.2008.07.066

Genes

ATF3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genomic variants of ATF3 in patients with hypospadias.PMID 18804813Read ↗

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