Article
Candidate genes and their response to environmental agents in the etiology of hypospadias.
Nature clinical practice. Urology - 1 May 2007
Willingham Emily, Baskin Laurence S
Abstract excerpt
The molecular events that lead to isolated hypospadias remain largely unknown, and the etiology of this common congenital anomaly seems to be multifactorial. We have explored the response of several candidate genes to environmental agents that cause hypospadias in a mouse model. Here, we provide an overview of current findings in relation to candidate genes and their response to environmental agents, including...
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