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Article

The tachykinin receptor 3 is associated with alcohol and cocaine dependence.

Alcoholism, clinical and experimental research - 1 Jun 2008

Foroud Tatiana, Wetherill Leah Flury, Kramer John, Tischfield Jay A, Nurnberger John I, Schuckit Marc A, Xuei Xiaoling, Edenberg Howard J

Abstract excerpt

BACKGROUND: A broad region on chromosome 4q was previously linked to the phenotype of alcohol dependence in the Collaborative Study on the Genetics of Alcoholism sample. A strong positional candidate gene was identified within this region: tachykinin receptor 3 gene (TACR3), which encodes tachykinin receptor 3 (NK3R), the receptor for the tachykinin 3 (neurokinin B) peptide. Pharmacological studies have provided...

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Identifiers

PMID: 18422838
DOI: 10.1111/j.1530-0277.2008.00663.x
PMCID: PMC2430628

Genes

TACR3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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