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Article

Histamine H3 receptor gene variants associated with drug abuse in patients with cocaine use disorder.

Journal of psychopharmacology (Oxford, England) - 1 Nov 2020

Pallardo-Fernández Iñigo, Muñoz-Rodríguez José Ramón, González-Martín Carmen, Alguacil Luis F

Abstract excerpt

BACKGROUND: Preclinical work revealed significant interactions between ligands of the histamine H3 receptor and different drugs of abuse. In the case of psychostimulants, the results reported are somewhat controversial and human data are still scarce, despite the fact that an inverse agonist of the H3 receptor (pitolisant) has reached the market after approval for the treatment of narcolepsy. AIMS: We have...

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PMID: 33063610
DOI: 10.1177/0269881120961253

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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