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Article

Neurexin 3 polymorphisms are associated with alcohol dependence and altered expression of specific isoforms.

Human molecular genetics - 1 Dec 2007

Hishimoto Akitoyo, Liu Qing-Rong, Drgon Tomas, Pletnikova Olga, Walther Donna, Zhu Xu-Guang, Troncoso Juan C, Uhl George R

Abstract excerpt

Neurexins are cell adhesion molecules that help to specify and stabilize synapses and provide receptors for neuroligins, neurexophilins, dystroglycans and alpha-latrotoxins. We previously reported significant allele frequency differences for single nucleotide polymorphisms (SNPs) in the neurexin 3 (NRXN3) gene in each of two comparisons between individuals who were dependent on illegal substances and controls. We...

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Source

Identifiers

PMID: 17804423
DOI: 10.1093/hmg/ddm247

Genes

NRXN3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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