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Article

Associations of NLRP3 and CARD8 gene polymorphisms with alcohol dependence and commonly related psychiatric disorders: a preliminary study.

Arhiv za higijenu rada i toksikologiju - 28 Sept 2021

Ilješ Anja Plemenitaš, Plesničar Blanka Kores, Dolžan Vita

Abstract excerpt

We investigated two functional polymorphisms in NLRP3 inflammasome genes (NLRP3 rs35829419 and CARD8 rs2043211) and their association with alcohol dependence and related anxiety, depression, obsession-compulsion, or aggression in 88 hospitalised alcohol-dependent patients, 99 abstinent alcohol-dependent participants, and 94 controls, all male Caucasian. Alcohol dependence-related psychiatric disorders were...

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Identifiers

PMID: 34587665
DOI: 10.2478/aiht-2021-72-3432
PMCID: PMC8576752

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