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Article

Dendritic cells pulsed with alpha-fetoprotein and mutant P53 fused gene induce bi-targeted cytotoxic T lymphocyte response against hepatic carcinoma.

Cancer science - 1 Jul 2008

Ren Jun, Jia Jun, Zhang Hongmei, Zhang Liwang, Ma Bo, Jiang Hanfang, Di Lijun, Song Guohong, Yu Jing

Abstract excerpt

Dendritic cell (DC)-based immunotherapy is rapidly emerging as a promising treatment in cancer therapy. We had previously shown that DC pulsed with either defined mRNA of tumor antigen (Ag) such as alpha-fetoprotein (AFP), or total RNA of hepatocellular carcinoma (HCC) could elicit Ag-specific cy...

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Identifiers

PMID: 18422751
DOI: 10.1111/j.1349-7006.2008.00820.x
PMCID: PMC11158406

Genes

AFP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18422751-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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