Article
Comparative analysis of DC fused with tumor cells or transfected with tumor total RNA as potential cancer vaccines against hepatocellular carcinoma.
Cytotherapy - 1 Jan 2006
Zhang Hong-Mei, Zhang Li-Wang, Liu Wen-Chao, Cheng Jie, Si Xiao-Ming, Ren Jun
Abstract excerpt
BACKGROUND: DC vaccination with the use of tumor cells provides the potential to generate a polyclonal immune response to multiple known and unknown tumor Ag. Our study comparatively analyzed DC fused with tumor cells or transfected with tumor total RNA as potential cancer vaccines against hepatocellular carcinoma (HCC). METHODS: Immature DC generated from PBMC of patients with HCC were fused with HepG2-GFP...
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