Article

Dendritic cells transfected with a polyepitope DNA construct stimulate an antitumor cytotoxic response in various tumor diseases

2021-07-13

Abstract excerpt

Dendritic cells (DCs) loaded with tumor-associated antigens (TAA) are known to be the important agents in antitumor response realization and still figure in lots of treatment schemes in cancer immunotherapy research. Here, we evaluated a cell-based protocol involving the use of original DNA constructs encoding the wide range of TAA epitopes expressed on different epithelial cancers. The constructs were transfected...

Topics

Open a Topic to create a Post that cites this publication.

Identifiers and source

Literature Corpus work: 451685c8-c354-5766-a209-be54bdf97741
DOI: 10.21203/rs.3.rs-696890/v1

Open publication

Related research

Semantic proximity does not establish scientific evidence.

Click a neighbor to travelStep 1 · 12 closest

Dendritic cells transfected with a polyepitope DNA construct stimulate an antitumor cytotoxic response in various tumor diseasesDOI 10.21203/rs.3.rs-696890/v1Read

Generation of multiple peptide cocktail-pulsed dendritic cells as a cancer vaccine.Semantic proximity Read

Development of Cell Technologies Based on Dendritic Cells for Immunotherapy of Oncological DiseasesSemantic proximity Read

Gene-modified dendritic cell vaccines for cancer.Semantic proximity Read

Dendritic-Tumor Fusion Cell-Based Cancer VaccinesSemantic proximity Read

Optimized mobilization of MHC class I- and II- restricted immunity by dendritic cell vaccine potentiates cancer therapySemantic proximity Read

Dendritic cells pulsed with RNA encoding allogeneic MHC and antigen induce T cells with superior antitumor activity and higher TCR functional aviditySemantic proximity Read

Dendritic Cell Strategies for Eliciting Mutation-Derived Tumor Antigen Responses in Patients.Semantic proximity Read

Active immunization against cancer with dendritic cells: the near future.Semantic proximity Read

Cancer immunotherapy with mRNA‐transfected dendritic cellsSemantic proximity Read

Equipping Cancer Cell Membrane Vesicles with Functional DNA as a Targeted Vaccine for Cancer ImmunotherapySemantic proximity Read

Clinical safety of induced CTL infusion through recombinant adeno-associated virus-transfected dendritic cell vaccination in Chinese cancer patients.Semantic proximity Read

Cellular Immunotherapy with Dendritic Cells in Cancer: Current StatusSemantic proximity Read