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Article

Immunoregulation of dendritic and T cells by alpha-fetoprotein in patients with hepatocellular carcinoma.

Journal of hepatology - 1 Dec 2004

Ritter Marcus, Ali Mona Y, Grimm Christian F, Weth Robert, Mohr Leonhard, Bocher Wulf O, Endrulat Katja, Wedemeyer Heiner, Blum Hubert E, Geissler Michael

Abstract excerpt

BACKGROUND/AIMS: Novel immunotherapeutic and other strategies are being explored for the treatment of hepatocellular carcinoma (HCC). Alpha-fetoprotein (AFP) may be a target antigen for immunotherapy. Little is known, however, about the immunobiology of AFP. Therefore, the impact of AFP on dendritic cells (DC), CD4+ and CD8+ T cells was studied in detail. METHODS: Immune cells from peripheral blood of 27 HCC...

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Share to alpha-Fetoproteins
Share to Antigens, CD

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Carcinoma, Hepatocellular

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Source

Identifiers

PMID: 15582134
DOI: 10.1016/j.jhep.2004.08.013

Genes

AFP

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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