Article

Nonviral mcDNA-Mediated Cospecific CAR T Cells For The Treatment of Human Hepatocellular Carcinoma Xenograft in Mice

2021-11-10

Abstract excerpt

<title>Abstract</title> <p><bold>Background: </bold>Hepatocellular carcinoma (HCC) is one of the most common cancers worldwide and the adoptive immunotherapy of which is worth studying. CD133, a kind of cancer stem cell (CSC) antigen, together with glypican-3 (GPC3) have been proved to be highly expressed in HCC cells and both of them are used as targets to generate chimeric antigen receptor (CAR) T cells. But th...

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Literature Corpus work: 4869b727-42c1-5955-8c72-f9fa85becd12
DOI: 10.21203/rs.3.rs-1039651/v1

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