Article
T cell responses to HLA-A*0201-restricted peptides derived from human alpha fetoprotein.
Journal of immunology (Baltimore, Md. : 1950) - 15 Apr 2001
Butterfield L H, Meng W S, Koh A, Vollmer C M, Ribas A, Dissette V B, Faull K, Glaspy J A, McBride W H, Economou J S
Abstract excerpt
alpha fetoprotein (AFP)-derived peptide epitopes can be recognized by human T cells in the context of MHC class I. We determined the identity of AFP-derived peptides, presented in the context of HLA-A*0201, that could be recognized by the human (h) T cell repertoire. We screened 74 peptides and identified 3 new AFP epitopes, hAFP(137-145), hAFP(158-166), and hAFP(325-334), in addition to the previously reported...
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