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Article

Branched multipeptide immunotherapy for glioblastoma using human leukocyte antigen-A*0201-restricted cytotoxic T-lymphocyte epitopes from ERBB2, BIRC5 and CD99.

Oncotarget - 2 Aug 2016

Kim Young-Hee, Tran Thi-Anh-Thuy, Lee Hyun-Ju, Jung Sook-In, Lee Je-Jung, Jang Wool-Youl, Moon Kyung-Sub, Kim In-Young, Jung Shin, Jung Tae-Young

Abstract excerpt

We investigated the use of cytotoxic T-lymphocyte (CTL) epitopes in peptide immunotherapy for glioblastoma. Three peptides (ERBB2, BIRC5 and CD99) were selected based on their peptide-T2 cell binding affinities and combined in a multipeptide cocktail or a branched multipeptide synthesized with mini-polyethylene glycol spacers. Dendritic cells (DCs) pulsed with the multipeptide cocktail or branched multipeptide...

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Share to Epitopes, T-Lymphocyte
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to HLA-A2 Antigen

Share to Inhibitor of Apoptosis Proteins

Share to L-Lactate Dehydrogenase

Share to Receptor, ErbB-2

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Share to T-Lymphocytes, Cytotoxic

Source

Open in PubMed Open full text

Identifiers

PMID: 27409668
DOI: 10.18632/oncotarget.10495
PMCID: PMC5226601

Genes

ERBB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 3 Sept 2026.

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