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Article

Human monocyte-derived dendritic cells pulsed with wild-type p53 protein efficiently induce CTLs against p53 overexpressing human cancer cells.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Feb 2005

Tokunaga Naoyuki, Murakami Takayoshi, Endo Yoshikatsu, Nishizaki Masahiko, Kagawa Shunsuke, Tanaka Noriaki, Fujiwara Toshiyoshi

Abstract excerpt

PURPOSE: Dendritic cells are the most potent antigen-presenting cells for initiating cellular immune responses. Dendritic cells are attractive immunoregulatory cells for cancer immunotherapy, and their efficacy has been investigated in clinical trials. The tumor suppressor gene p53 is pivotal in the regulation of apoptosis, and p53-based immunization is an attractive approach to cancer immunotherapy because of...

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PMID: 15709203

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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