Article
The MUT9p kinase phosphorylates histone H3 threonine 3 and is necessary for heritable epigenetic silencing in Chlamydomonas.
Proceedings of the National Academy of Sciences of the United States of America - 29 Apr 2008
Casas-Mollano J Armando, Jeong Byeong-Ryool, Xu Jianping, Moriyama Hideaki, Cerutti Heriberto
Abstract excerpt
Changes in chromatin organization are emerging as key regulators in nearly every aspect of DNA-templated metabolism in eukaryotes. Histones undergo many, largely reversible, posttranslational modifications that affect chromatin structure. Some modifications, such as trimethylation of histone H3 on Lys 4 (H3K4me3), correlate with transcriptional activation, whereas others, such as methylation of histone H3 on Lys...
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