Article
Protein phosphatase PP1 is required for normal DNA methylation in Neurospora.
Genes & development - 15 Dec 2008
Adhvaryu Keyur K, Selker Eric U
Abstract excerpt
Covalent modifications of histones integrate intracellular and extracellular cues to regulate the genome. H3 Lys 9 methylation (H3K9me) can direct heterochromatin formation and DNA methylation, while phosphorylation of H3 Ser 10 (H3S10p) drives gene activation and chromosome condensation. To examine the relationship between H3S10p, H3K9me, and DNA methylation in Neurospora crassa, we built and tested mutants of...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
