Article
H3T11 phosphorylation by CKII is required for heterochromatin formation in Neurospora.
Nucleic acids research - 9 Sept 2024
Tian Yuan, Zhang Chengcheng, Tian Xiang, Zhang Lu, Yin Tong, Dang Yunkun, Liu Yi, Lou Huiqiang, He Qun
Abstract excerpt
Heterochromatin is a key feature of eukaryotic genomes and is crucial for maintaining genomic stability. In fission yeast, heterochromatin nucleation is mainly mediated by DNA-binding proteins or the RNA interference (RNAi) pathway. In the filamentous fungus Neurospora crassa, however, the mechanism that causes the initiation of heterochromatin at the relics of repeat-induced point mutation is unknown and...
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