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Article

Coronavirus nonstructural protein 16 is a cap-0 binding enzyme possessing (nucleoside-2'O)-methyltransferase activity.

Journal of virology - 1 Aug 2008

Decroly Etienne, Imbert Isabelle, Coutard Bruno, Bouvet Mickaël, Selisko Barbara, Alvarez Karine, Gorbalenya Alexander E, Snijder Eric J, Canard Bruno

Abstract excerpt

The coronavirus family of positive-strand RNA viruses includes important pathogens of livestock, companion animals, and humans, including the severe acute respiratory syndrome coronavirus that was responsible for a worldwide outbreak in 2003. The unusually complex coronavirus replicase/transcriptase is comprised of 15 or 16 virus-specific subunits that are autoproteolytically derived from two large polyproteins....

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Identifiers

PMID: 18417574
DOI: 10.1128/JVI.00407-08
PMCID: PMC2519555

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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