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A High-Throughput Radioactivity-Based Assay for Screening SARS-CoV-2 nsp10-nsp16 Complex

20 Apr 2021

Abstract excerpt

Frequent outbreaks of novel coronaviruses (CoVs), highlighted by the current severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) pandemic, necessitate the development of therapeutics that could be easily and effectively administered worldwide. The conserved mRNA-capping process enables CoVs to evade their host immune system and is a target for antiviral development. Nonstructural protein (nsp) 16 in...

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PMID: 33874769
DOI: 10.1177/24725552211008863

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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