Article

SARS-CoV-2 Uses Nonstructural Protein 16 to Evade Restriction by IFIT1 and IFIT3

2022-09-26

Abstract excerpt

Understanding the molecular basis of innate immune evasion by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) is an important consideration for designing the next wave of therapeutics. Here, we investigate the role of the nonstructural protein 16 (NSP16) of SARS-CoV-2 in infection and pathogenesis. NSP16, a ribonucleoside 2’- O methyltransferase (MTase), catalyzes the transfer of a methyl group to mR...

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Literature Corpus work: 63aad26f-4559-5ddf-9973-f9ff220fce1f
DOI: 10.1101/2022.09.26.509529

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