CD14 tobacco gene-environment interaction modifies asthma severity and immunoglobulin E levels in Latinos with asthma.

doi:10.1164/rccm.200409-1232OC

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Article

CD14 tobacco gene-environment interaction modifies asthma severity and immunoglobulin E levels in Latinos with asthma.

American journal of respiratory and critical care medicine - 15 Jul 2005

Choudhry Shweta, Avila Pedro C, Nazario Sylvette, Ung Ngim, Kho Jennifer, Rodriguez-Santana Jose R, Casal Jesus, Tsai Hui-Ju, Torres Alfonso, Ziv Elad, Toscano Monica, Sylvia Jody Senter, Alioto Mariaelena, Salazar Michael, Gomez Ivan, Fagan Joanne K, Salas Jorge, Lilly Craig, Matallana Henry, Castro Richard A, Selman Moises, Weiss Scott T, Ford Jean G, Drazen Jeffrey M, Rodriguez-Cintron William, Chapela Rocio, Silverman Edwin K, Burchard Esteban González

Abstract excerpt

BACKGROUND: A recent family-based genomewide screen revealed linkage between the 5q31 region and the diagnosis of asthma, but only in those exposed to environmental tobacco smoke (ETS). Among the candidate genes in this region is CD14. METHODS: To determine whether polymorphisms in the CD14 gene are related to this gene-by-environment interaction in Latinos, we used both family-based and cross-sectional cohort...

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Identifiers

PMID: 15879416
DOI: 10.1164/rccm.200409-1232OC

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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