Article
A methodology to establish a database to study gene environment interactions for childhood asthma.
BMC medical research methodology - 6 Dec 2010
Turner Stephen W, Ayres Jon G, Macfarlane Tatiana V, Mehta Anil, Mehta Gita, Palmer Colin N, Cunningham Steve, Adams Tim, Aniruddhan Krishnan, Bell Claire, Corrigan Donna, Cunningham Jason, Duncan Andrew, Hunt Gerard, Leece Richard, MacFadyen Una, McCormick Jonathan, McLeish Sally, Mitra Andrew, Miller Deborah, Waxman Elizabeth, Webb Alan, Wojcik Slawomir, Mukhopadhyay Somnath, Macgregor Donald
Abstract excerpt
BACKGROUND: Gene-environment interactions are likely to explain some of the heterogeneity in childhood asthma. Here, we describe the methodology and experiences in establishing a database for childhood asthma designed to study gene-environment interactions (PAGES--Paediatric Asthma Gene Environment Study). METHODS: Children with asthma and under the care of a respiratory paediatrician are being recruited from 15...
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