Article
Gene-environment interactions in asthma and allergies: a new paradigm to understand disease causation.
Immunology and allergy clinics of North America - 1 Nov 2005
Martinez Fernando D
Abstract excerpt
The example of complex interactions between environmental exposures and polymorphisms in the CD14 gene in predisposing for allergy-related conditions offers a good indication of the complexity of the mechanisms that determine susceptibility to these conditions. Contrary to what has been the rule for monogenic diseases, the association between genetic variations and polygenic conditions such as asthma and...
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