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Article

Study of DHPS and DHFR genes of Pneumocystis jirovecii in Thai HIV-infected patients.

Medical mycology - 1 Jun 2008

Siripattanapipong Suradej, Leelayoova Saovanee, Mungthin Mathirut, Worapong Jeerapun, Tan-Ariya Peerapan

Abstract excerpt

The combination of trimethoprim-sulfamethoxazole is widely used for the prophylaxis and treatment of Pneumocystis pneumonia (PCP) caused by Pneumocystis jirovecii. Many studies have shown that mutations in the drug target, the dihydropteroate synthase (DHPS) gene, are presumably involved with the failure of prophylaxis and treatment. We have analyzed dihydropteroate synthase (DHPS) and dihydrofolate reductase...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to DNA, Fungal

Share to Pneumocystis carinii

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Source

Identifiers

PMID: 18415849
DOI: 10.1080/13693780701883722

Genes

DHPS
DHFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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