Deviation from the random distribution pattern of influenza A virus gene segments in reassortants produced under non-selective conditions.

doi:10.1007/s00705-008-0070-5

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Article

Deviation from the random distribution pattern of influenza A virus gene segments in reassortants produced under non-selective conditions.

Archives of virology - 1 Jan 2008

Varich N L, Gitelman A K, Shilov A A, Smirnov Y A, Kaverin N V

Abstract excerpt

High-frequency reassortment of gene segments is characteristic for influenza viruses, and it is considered to be of significance for the origin of pandemic influenza. In order to analyze whether the segregation of genes in the reassortants is random, or it deviates from the random pattern, we inoculated embryonated chicken eggs simultaneously with two influenza viruses, A/WSN/33 (H1N1) and A/Duck/...

Topics

Animals
Cell Line
Chick Embryo
Genes, Viral
Genetic Variation
Hemagglutinins, Viral
Influenza A virus
Reassortant Viruses
Viral Core Proteins

Source

Open in PubMed

Identifiers

PMID: 18414973
DOI: 10.1007/s00705-008-0070-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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