Analysis on reassortment of rotavirus NSP1 genes lacking coding region for cysteine-rich zinc finger motif.

doi:10.1007/s007050050508

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Article

Analysis on reassortment of rotavirus NSP1 genes lacking coding region for cysteine-rich zinc finger motif.

Archives of virology - 1 Jan 1999

Okada J, Kobayashi N, Taniguchi K, Urasawa S

Abstract excerpt

Rotavirus clones A5-10 and A5-16 isolated from a bovine rotavirus strain A5 possess NSP1 gene which has a point mutation generating a nonsense codon and a 500 base-deletion, respectively. As a result, the two A5 clones encode truncated NSP1 product which lacks cysteine-rich region forming zinc finger motif. In order to analyze reassortment of these mutated NSP1 gene with RNA segments from heterologous strains, we...

Topics

Animals
Cattle
Cell Line
Cysteine
Genotype
Humans
Mutation
RNA, Viral
Reassortant Viruses
Recombination, Genetic
Rotavirus
Viral Nonstructural Proteins
Virus Replication
Zinc Fingers

Source

Open in PubMed

Identifiers

PMID: 10470258
DOI: 10.1007/s007050050508

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026.

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