Article
Analysis on reassortment of rotavirus NSP1 genes lacking coding region for cysteine-rich zinc finger motif.
Archives of virology - 1 Jan 1999
Okada J, Kobayashi N, Taniguchi K, Urasawa S
Abstract excerpt
Rotavirus clones A5-10 and A5-16 isolated from a bovine rotavirus strain A5 possess NSP1 gene which has a point mutation generating a nonsense codon and a 500 base-deletion, respectively. As a result, the two A5 clones encode truncated NSP1 product which lacks cysteine-rich region forming zinc finger motif. In order to analyze reassortment of these mutated NSP1 gene with RNA segments from heterologous strains, we...
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