Article
Critical role of segment-specific packaging signals in genetic reassortment of influenza A viruses.
Proceedings of the National Academy of Sciences of the United States of America - 1 Oct 2013
Essere Boris, Yver Matthieu, Gavazzi Cyrille, Terrier Olivier, Isel Catherine, Fournier Emilie, Giroux Fabienne, Textoris Julien, Julien Thomas, Socratous Clio, Rosa-Calatrava Manuel, Lina Bruno, Marquet Roland, Moules Vincent
Abstract excerpt
The fragmented nature of the influenza A genome allows the exchange of gene segments when two or more influenza viruses infect the same cell, but little is known about the rules underlying this process. Here, we studied genetic reassortment between the A/Moscow/10/99 (H3N2, MO) virus originally isolated from human and the avian A/Finch/England/2051/91 (H5N2, EN) virus and found that this process is strongly...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
