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Article

Effect of the selection pressure with anti-VP7 and anti-VP4 neutralizing monoclonal antibodies on reassortant formation between two human rotaviruses.

Archives of virology - 1 Jan 1994

Kobayashi N, Taniguchi K, Urasawa T, Urasawa S

Abstract excerpt

In order to study the effect of selection pressure of anti-VP4 and anti-VP7 neutralizing monoclonal antibodies(N-MAbs) on reassortant formation, 424 reassortant clones were produced from mixed cultures of human rotavirus strains Wa and HN126 and their genotypes were analysed. Reassortant selection was done with four types of N-MAb: anti-VP4 MAb to Wa and anti-VP7 MAb to HN126(selection A); anti-VP4 MAb to HN126...

Topics

Antibodies, Monoclonal
Antigens, Viral
Capsid
Capsid Proteins
Cell Line
Genotype
Humans
Neutralization Tests
RNA, Viral
Rotavirus
Selection, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Serotyping

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Identifiers

PMID: 7802855
DOI: 10.1007/BF01310022

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7802855-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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Effect of the selection pressure with anti-VP7 and anti-VP4 neutralizing monoclonal antibodies on reassortant formation between two human rotaviruses.PMID 7802855Read ↗

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