Article
Effect of gene constellation and postreassortment amino acid change on the phenotypic features of H5 influenza virus reassortants.
Archives of virology - 1 Jan 2007
Rudneva I A, Timofeeva T A, Shilov A A, Kochergin-Nikitsky K S, Varich N L, Ilyushina N A, Gambaryan A S, Krylov P S, Kaverin N V
Abstract excerpt
Reassortants between a low-pathogenic avian influenza virus strain A/Duck/Primorie/2621/2001 (H5N2) and a high-yield human influenza virus strain A/Puerto Rico/8/34 (H1N1) were generated, genotyped and analyzed with respect to their yield in embryonated chicken eggs, pathogenicity for mice, and immunogenicity. A reassortant having HA and NA genes from A/Duck/Primorie/2621/2001 virus and 6 genes from A/Puerto...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
