Article
Preferential selection of specific rotavirus gene segments in coinfection and multiple passages with reassortant viruses and their parental strain.
Research in virology - 1 Jan 2000
Kobayashi N, Taniguchi K, Urasawa T, Urasawa S
Abstract excerpt
We previously reported non-random selections of human rotavirus (HRV) Wa genes 2 and 5 in reassortant formation between HRV strains Wa and HN126 under selection pressure with neutralizing monoclonal antibodies. In order to study whether or not these genes are preferentially selected in the genetic background of a parental strain HN126 in vitro without selection pressures, coinfection and multiple passage...
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