Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Kidney injury molecule-1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells.

The Journal of clinical investigation - 1 May 2008

Ichimura Takaharu, Asseldonk Edwin J P V, Humphreys Benjamin D, Gunaratnam Lakshman, Duffield Jeremy S, Bonventre Joseph V

Abstract excerpt

Following injury, the clearance of apoptotic and necrotic cells is necessary for mitigation and resolution of inflammation and tissue repair. In addition to macrophages, which are traditionally assigned to this task, neighboring epithelial cells in the affected tissue are postulated to contribute to this process. Kidney injury molecule-1 (KIM-1 or TIM-1) is an immunoglobulin superfamily cell-surface protein not...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Bone Marrow Cells
Share to Cell Adhesion Molecules

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Epithelial Cells

Share to Kidney Tubules

Share to Lipoproteins, LDL

Share to Phagocytosis

Share to Phosphatidylserines

Share to Receptors, Cell Surface

Source

Open in PubMed Open full text

Identifiers

PMID: 18414680
DOI: 10.1172/JCI34487
PMCID: PMC2293335

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Kidney injury molecule-1 is a phosphatidylserine receptor that confers a phagocytic phenotype on epithelial cells.PMID 18414680Read ↗

The role of macrophages during acute kidney injury: destruction and repair.Semantic proximity Read ↗

ELMO1 dependent efferocytosis protects from nephrotoxin induced acute kidney injurySemantic proximity Read ↗

Macrophages in the kidney in health, injury and repair.Semantic proximity Read ↗

Chronic epithelial kidney injury molecule-1 expression causes murine kidney fibrosis.Semantic proximity Read ↗

Pathogenic and protective role of macrophages in kidney disease.Semantic proximity Read ↗

Dendritic Cells and Macrophages: Sentinels in the Kidney.Semantic proximity Read ↗

Dendritic cells and macrophages in the kidney: a spectrum of good and evil.Semantic proximity Read ↗

Macrophage phenotype controls long-term AKI outcomes--kidney regeneration versus atrophy.Semantic proximity Read ↗

Inflammation-mediated Upregulation of VCAM-1 but not KIM-1 during Acute Kidney Injury to Chronic Kidney Disease TransitionSemantic proximity Read ↗

Resident macrophages reprogram toward a developmental state after acute kidney injurySemantic proximity Read ↗

Renal F4/80+ CD11c+ mononuclear phagocytes display phenotypic and functional characteristics of macrophages in health and in adriamycin nephropathy.Semantic proximity Read ↗

Distinct macrophage phenotypes contribute to kidney injury and repair.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.