Article
The role of macrophages during acute kidney injury: destruction and repair.
Pediatric nephrology (Berlin, Germany) - 1 Apr 2019
Han Hwa I, Skvarca Lauren B, Espiritu Eugenel B, Davidson Alan J, Hukriede Neil A
Abstract excerpt
Acute kidney injury (AKI) is defined by a rapid decline in renal function. Regardless of the initial cause of injury, the influx of immune cells is a common theme during AKI. While an inflammatory response is critical for the initial control of injury, a prolonged response can negatively affect tissue repair. In this review, we focus on the role of macrophages, from early inflammation to resolution, during AKI....
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