Article
The quest for the 1p36 tumor suppressor.
Cancer research - 15 Apr 2008
Bagchi Anindya, Mills Alea A
Abstract excerpt
Genomic analyses of late-stage human cancers have uncovered deletions encompassing 1p36, thereby providing an extensive body of literature supporting the idea that a potent tumor suppressor resides in this interval. Although several genes have been proposed as 1p36 candidate tumor suppressors, convincing evidence that their encoded products protect from cancer has been scanty. A recent functional study identified...
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