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Article

Diversity roles of CHD1L in normal cell function and tumorigenesis

4 Mar 2021

Abstract excerpt

Chromodomain helicase/ATPase DNA binding protein 1-like gene (CHD1L) is a multifunctional protein participated in diverse cellular processes, including chromosome remodeling, cell differentiation and development. CHD1L is a regulator of chromosomal integrity maintenance, DNA repair and transcriptional regulation through its bindings to DNA. By regulating kinds of complex networks, CHD1L has been identified as a...

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PMID: 33663617
DOI: 10.1186/s40364-021-00269-w

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