Article
Crystal structure of the Mus81-Eme1 complex.
Genes & development - 15 Apr 2008
Chang Jeong Ho, Kim Jeong Joo, Choi Jung Min, Lee Jung Hoon, Cho Yunje
Abstract excerpt
The Mus81-Eme1 complex is a structure-specific endonuclease that plays an important role in rescuing stalled replication forks and resolving the meiotic recombination intermediates in eukaryotes. We have determined the crystal structure of the Mus81-Eme1 complex. Both Mus81 and Eme1 consist of a central nuclease domain, two repeats of the helix-hairpin-helix (HhH) motif at their C-terminal region, and a linker...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
