Article
Neurovascular control during exercise in acute coronary syndrome patients with Gln27Glu polymorphism of β2-adrenergic receptor.
PloS one - 1 Jan 2017
Ferreira-Santos Larissa, Martinez Daniel G, Nicolau José Carlos, Moreira Humberto G, Alves Maria Janieire, Pereira Alexandre C, Trombetta Ivani C, Negrão Carlos Eduardo, Rondon Maria Urbana P B
Abstract excerpt
BACKGROUND: Gln27Glu (rs1042714) polymorphism of the β2-adrenergic receptor (ADRB2) has been association with cardiovascular functionality in healthy subjects. However, it is unknown whether the presence of the ADRB2 Gln27Glu polymorphism influences neurovascular responses during exercise in patients with acute coronary syndromes (ACS). We tested the hypothesis that patients with ACS homozygous for the Gln allele...
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