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Article

A novel GWAS locus influences microvascular response to mental stress and predicts adverse cardiovascular events.

Scientific reports - 8 Oct 2024

Almuwaqqat Zakaria, Liu Chang, Kim Jeong Hwan, Hammadah Muhammad, Alkhoder Ayman, Raggi Paolo, Shah Amit J, Bremner J Douglas, Vaccarino Viola, Sun Yan V, Quyyumi Arshed A

Abstract excerpt

Excessive peripheral microvascular constriction during acute psychological stress reflects similar changes in coronary blood flow and is a predictor of adverse cardiovascular outcomes. Among individuals with coronary artery disease (CAD), we sought to determine if genetic factors contribute to the degree of microvascular constriction during mental stress. A total of 580 stable CAD individuals from two prospective...

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Identifiers

PMID: 39379420
DOI: 10.1038/s41598-024-54566-z
PMCID: PMC11461842

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CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

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