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Article

Cerebral amyloid angiopathy and parenchymal amyloid deposition in transgenic mice expressing the Danish mutant form of human BRI2.

Brain pathology (Zurich, Switzerland) - 1 Jan 2009

Vidal Ruben, Barbeito Ana G, Miravalle Leticia, Ghetti Bernardino

Abstract excerpt

Familial Danish dementia (FDD) is an autosomal dominant neurodegenerative disease clinically characterized by the presence of cataracts, hearing impairment, cerebellar ataxia and dementia. Neuropathologically, FDD is characterized by the presence of widespread cerebral amyloid angiopathy (CAA), parenchymal amyloid deposition and neurofibrillary tangles. FDD is caused by a 10-nucleotide duplication-insertion in...

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Identifiers

PMID: 18410407
DOI: 10.1111/j.1750-3639.2008.00164.x
PMCID: PMC2605177

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

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