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Article

Osteopontin promoter polymorphism is associated with increased carotid intima-media thickness.

Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography - 1 Aug 2008

de las Fuentes Lisa, Gu C Charles, Mathews Santhosh J, Reagan Joann L, Ruthmann Nicholas P, Waggoner Alan D, Lai Chung-Fang, Towler Dwight A, Dávila-Román Víctor G

Abstract excerpt

BACKGROUND: Osteopontin (OPN)-transgenic mice exhibit increased carotid artery intima-media thickness (CIMT), smooth muscle cell proliferation, and atheroma formation. METHODS: An association of the human T-66G promoter variant with CIMT was examined in Caucasian adults grouped according to metab...

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Source

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Identifiers

PMID: 18406574
DOI: 10.1016/j.echo.2008.02.005
PMCID: PMC2536614

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-18406574-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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