Article
Polymorphism rs2073618 of the osteoprotegerin gene as a potential marker of subclinical carotid atherosclerosis in Caucasians with type 2 diabetes mellitus.
VASA. Zeitschrift fur Gefasskrankheiten - 1 Aug 2017
Pleskovič Aleš, Ramuš Sara Mankoč, Pražnikar Zala Jenko, Šantl Letonja Marija, Cokan Vujkovac Andreja, Gazdikova Katarina, Caprnda Martin, Gaspar Ludovit, Kruzliak Peter, Petrovič Daniel
Abstract excerpt
BACKGROUND: The OPG/RANKL/RANK (osteoprotegerin/receptor-activator of nuclear factor κB ligand/receptor-activator of nuclear factor κB) axis has been recently linked to the development of atherosclerosis and plaque destabilization. We have investigated whether polymorphism rs2073618 of the OPG gene is associated with subclinical markers of carotid atherosclerosis in subjects with type 2 diabetes mellitus (T2DM)....
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