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Article

Genetic variation in PPARG encoding peroxisome proliferator-activated receptor gamma associated with carotid atherosclerosis.

Stroke - 1 Sept 2004

Al-Shali Khalid Z, House Andrew A, Hanley Anthony J G, Khan Hafiz M R, Harris Stewart B, Zinman Bernard, Mamakeesick Mary, Fenster Aaron, Spence J David, Hegele Robert A

Abstract excerpt

BACKGROUND AND PURPOSE: Peroxisome proliferator-activated receptor gamma is a crucial molecule in atherogenesis because it is associated with metabolic risk factors such as obesity and diabetes and also plays a key role in subcellular metabolism of arterial wall macrophage foam cells. Genetic variation in PPARG has been associated with metabolic and cardiovascular end points. METHODS: We investigated the...

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Source

Identifiers

PMID: 15284449
DOI: 10.1161/01.STR.0000138784.68159.a5

Genes

PPARG

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Genetic variation in PPARG encoding peroxisome proliferator-activated receptor gamma associated with carotid atherosclerosis.PMID 15284449Read ↗

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