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Article

Genetic variability of the mu-opioid receptor influences intrathecal fentanyl analgesia requirements in laboring women.

Pain - 30 Sept 2008

Landau Ruth, Kern Christian, Columb Malachy O, Smiley Richard M, Blouin Jean-Louis

Abstract excerpt

Labor initiates one of the most intensely painful episodes in a woman's life. Opioids are used to provide analgesia with substantial interindividual variability in efficacy. mu-Opioid receptor (muOR, OPRM1) genetic variants may explain differences in response to opioid analgesia. We hypothesized...

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Source

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Identifiers

PMID: 18403122
DOI: 10.1016/j.pain.2008.02.023
PMCID: PMC2669083

Genes

OPRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-18403122-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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