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Article

The effect of OPRM1 and COMT genotypes on the analgesic response to intravenous fentanyl labor analgesia.

Anesthesia and analgesia - 1 Feb 2013

Landau Ruth, Liu Shih-Kai, Blouin Jean-Louis, Carvalho Brendan

Abstract excerpt

BACKGROUND: IV fentanyl is used as a labor analgesic; however, few studies have reported the effects of IV fentanyl for early labor analgesia. We evaluated the analgesic response to IV fentanyl according to the combined effect of the single-nucleotide polymorphisms rs1799971 (c.118A/G, p. 40Asn/Asp) of the µ-opioid receptor gene (OPRM1) and rs4680 (c.472G/A, p.158Val/Met) of the catechol-O-methyltransferase...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 23302985
DOI: 10.1213/ANE.0b013e318273f2c7

Genes

COMT
OPRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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