Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic contributions to labor pain and progress.

Clinics in perinatology - 1 Sept 2013

Landau Ruth

Abstract excerpt

Studies on genetic contributions to labor analgesia have essentially evaluated the μ-opioid receptor gene (OPRM1), with some evidence that p.118A/G of OPRM1 influences the response to neuraxial opioids. As for labor progress, the β2-adrenergic receptor gene (ADRB2) is associated with preterm labor and delivery, and impacts the course of labor. Taken together though, there is no evidence that pharmacogenetic...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Analgesics, Opioid
Share to Catechol O-Methyltransferase
Share to Fentanyl

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Obstetric Labor, Premature

Share to Premature Birth

Share to Receptors, Adrenergic, beta-2

Share to Receptors, Opioid, mu

Share to Receptors, Oxytocin

Source

Identifiers

PMID: 23972758
DOI: 10.1016/j.clp.2013.05.014

Genes

OPRM1
ADRB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic contributions to labor pain and progress.PMID 23972758Read ↗

Pharmacogenetics in obstetric anesthesia.Semantic proximity Read ↗

β2-adrenergic receptor genotype and other variables that contribute to labor pain and progress.Semantic proximity Read ↗

Pharmacogenetics in obstetric anesthesia.Semantic proximity Read ↗

Genetic variability of the mu-opioid receptor influences intrathecal fentanyl analgesia requirements in laboring women.Semantic proximity Read ↗

Polymorphism in the ADRB2 gene explains a small portion of intersubject variability in pain relative to cervical dilation in the first stage of labor.Semantic proximity Read ↗

Observational study of the effect of mu-opioid receptor genetic polymorphism on intrathecal opioid labor analgesia and post-cesarean delivery analgesia.Semantic proximity Read ↗

Genetics and Gender in Acute Pain and Perioperative Opioid Analgesia.Semantic proximity Read ↗

Role of OPRM1, clinical and anthropometric variants in neonatal pain reduction.Semantic proximity Read ↗

Effects of OPRM1 A118G polymorphism on epidural analgesia with fentanyl during labor: a meta-analysis.Semantic proximity Read ↗

The A118G single-nucleotide polymorphism of human μ-opioid receptor gene and use of labor analgesia.Semantic proximity Read ↗

µ-opioid receptor gene variant OPRM1 118 A>G: a summary of its molecular and clinical consequences for pain.Semantic proximity Read ↗

Genetic contributions to clinical pain and analgesia: avoiding pitfalls in genetic research.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.